More dodgy papers for National University of Singapore to investigate

Update: 31st October 2011: Further dodgy papers are given in the next instalment from Abnormal Science.

Japanese Retraction Watch has also been on the case.

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Abnormal Science ( Joerg Zwirner) has 3 more examples of papers with some questionable images. This time the papers are from the Department of Physiology, National University of Singapore with 2 papers published in Blood and one in the Journal of Biological Chemistry.

The three papers tagged are:

1. Pervaiz S, Seyed MA, Hirpara JL, Clément MV, Loh KW.
Purified photoproducts of merocyanine 540 trigger cytochrome C release and caspase 8-dependent apoptosis in human leukemia and melanoma cells.
Blood. 1999 Jun 15;93(12):4096-108.
Department of Physiology, National University of Singapore; and the Oncology Research Institute, NUMI, Singapore

2. Hirpara JL, Seyed MA, Loh KW, Dong H, Kini RM, Pervaiz S.
Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells.
Blood. 2000 Mar 1;95(5):1773-80.
Department of Physiology, National University of Singapore, Singapore.

3. Hirpara JL, Clément MV, Pervaiz S.
Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells.
J Biol Chem. 2001 Jan 5;276(1):514-21.
Department of Physiology, National University of Singapore, Singapore

The two names common to all 3 papers are JL Hirpara and research supervisor Professor Shazib Pervaiz.

The NUS investigation committee has its work cut out with all the questionable papers they need to check out (See here and here).

As Abnormal Science puts it:

Their inquiry commissions might soon run out of unbiased members. NUS should consider to accept assistance from abroad to clean up the mess.

And it seems to be truly a mess covering a number of departments which indicates a prevailing culture and not just some isolated incident of wrongdoing.

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2 Responses to “More dodgy papers for National University of Singapore to investigate”

  1. A de Novo Says:

    Here are some more NUS retractions from a web search (not necessarily arising from internal investigations)

    Year of Retraction 2011:
    Chan, J Clinical Nursing (2011) 20:979 (DOI 10.1111/j.1365.2702.2010.03368.x
    Author from NUS

    Year of Retraction: 2010
    Le et al., Appl Phys Lett (2010) 97:239903 (DOI 10.1063/1.3512959),
    retracting Le et al., Appl Phys Lett (2005) 87:101908.
    Authors from NUS, ASTAR & NTU

    Year of Retraction: 2009
    Yang et al., American Institute of Chemical Engineers Journal (AIChE J) (2009) 55:2756 (DOI 10.1002/aic),
    retracting Yang et al., AIChE J (2006) 52:3266-3277 (DOI 10.1002/aic.10947).
    Authors from NUS

    Year of Retraction: 2007
    Ngo et al., Opt Quant Electron (2007) 39:707 (DOI 10.1007/s11082-007-9120-6),
    retracting Ngo et., Opt Quant Electron (2007) 38:981-991 (DOI 10.1007/s11082.006-9027-7).
    Authors from NUS, ASTAR & NTU

  2. Investigations of misconduct at Singapore need to be seen to be impartial « The k2p blog Says:

    […] saga of potential misconduct at the National University of Singapore continues to escalate with further […]

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