Posts Tagged ‘Nobel Prize in Physiology or Medicine’

Breaking! Nobel laureate Steinman died last Friday — and posthumous awards are not allowed.

October 3, 2011

UPDATE 2! Steinman will keep his award. 

 The Nobel foundation said in a statement:

The decision to award the 2011 Nobel Prize in Physiology or Medicine to the late Ralph Steinman shall remain unchanged, in keeping with the earlier announcement from the Nobel Assembly at Karolinska Institutet.

As announced earlier, Ralph Steinman – one of this year’s three Nobel Laureates in Physiology or Medicine – died on September 30. This information reached the Nobel Assembly at Karolinska Institutet via the president of Rockefeller University, where Steinman worked, at 14.30 CET on October 3, 2011. Earlier the same day, at 11.30 CET, the Nobel Assembly had announced the 2011 Nobel Laureates in Physiology or Medicine without knowing of Ralph Steinman’s death. 

The events that have occurred are unique and, to the best of our knowledge, are unprecedented in the history of the Nobel Prize. In light of this, the Board of the Nobel Foundation has held a meeting this afternoon. According to the statutes of the Nobel Foundation, work produced by a person since deceased shall not be given an award. However, the statutes specify that if a person has been awarded a prize and has died before receiving it, the prize may be presented.

An interpretation of the purpose of this rule leads to the conclusion that Ralph Steinman shall be awarded the 2011 Nobel Prize in Physiology or Medicine. The purpose of the above-mentioned rule is to make it clear that the Nobel Prize shall not deliberately be awarded posthumously. However, the decision to award the Nobel Prize to Ralph Steinman was made in good faith, based on the assumption that the Nobel Laureate was alive. This was true – though not at the time of the decision – only a day or so previously. The Nobel Foundation thus believes that what has occurred is more reminiscent of the example in the statutes concerning a person who has been named as a Nobel Laureate and has died before the actual Nobel Prize Award Ceremony.

The decision made by the Nobel Assembly at Karolinska Institutet thus remains unchanged.

UPDATE!

Press release: It is with deep sadness and regret that the Nobel Assembly at Karolinska Institutet has learned that Professor Ralph Steinman, one of this year´s three Nobel Laureates in Physiology or Medicine, passed away on September 30. This message was conveyed by The President of The Rockefeller University, where Professor Steinman worked, at 2.30 pm (CET), Monday October 3, 2011, after the decision and announcement about this year´s Nobel prize in Physiology or Medicine. Our thoughts are with Ralph Steinman´s family and colleagues.

The Nobel Assembly, consisting of 50 professors at Karolinska Institutet, awards the Nobel Prize in Physiology or Medicine. Its Nobel Committee evaluates the nominations. Since 1901 the Nobel Prize has been awarded to scientists who have made the most important discoveries for the benefit of mankind.

BBC reports: In 1931, Erik Axel Karlfeldt was posthumously awarded the Nobel prize for literature, but the rules were changed in 1974. The Nobel Foundation states: “Work produced by a person since deceased shall not be considered for an award. If, however, a prizewinner dies before he has received the prize, then the prize may be presented.” This happened in 1996 when William Vickrey died between the announcement and the prize ceremony.

The issue is being discussed at the moment and a decision should be made by Tuesday.

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This morning Ralph M. Steinman was one of 3 scientists awarded the Nobel prize for medicine ”for his discovery of the dendritic cell and its role in adaptive immunity“.

Swedish Radio has just announced that Prof. Steinman apparently passed away last Friday and the Nobel Awards committee was not aware of this when they announced the awards today. He died of cancer which he had been suffering from for the last 4 years. He passed away without knowing he had been awarded the prize.

The Nobel rules do not allow for posthumous awards and there is now some confusion as to whether Steinman will be a Nobel laureate or not.

Ralph M. Steinman was born in 1943 in Montreal, Canada, where he studied biology and chemistry at McGill University. After studying medicine at Harvard Medical School in Boston, MA, USA, he received his MD in 1968. He has been affiliated with Rockefeller University in New York since 1970, has been professor of immunology at this institution since 1988, and is also director of its Center for Immunology and Immune Diseases.

Portrait of Professor Ralph M. Steinman

Professor Ralph M. Steinman 1943 - 2011

Nobel Prize in Physiology or Medicine awarded – half to Beutler and Hoffman and half to Steinman

October 3, 2011

The 2011 Nobel Prize in Physiology or Medicine was awarded today and the 3 winners are in the field of immunology.

The prize was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann “for their discoveries concerning the activation of innate immunity” and the other half to Ralph M. Steinman “for his discovery of the dendritic cell and its role in adaptive immunity“.

The Thomson Reuter predictions – this time – missed the mark.

Official press release here. 

Summary

This year’s Nobel Laureates have revolutionized our understanding of the immune system by discovering key principles for its activation.

Scientists have long been searching for the gatekeepers of the immune response by which man and other animals defend themselves against attack by bacteria and other microorganisms. Bruce Beutler and Jules Hoffmann discovered receptor proteins that can recognize such microorganisms and activate innate immunity, the first step in the body’s immune response. Ralph Steinman discovered the dendritic cells of the immune system and their unique capacity to activate and regulate adaptive immunity, the later stage of the immune response during which microorganisms are cleared from the body.

The discoveries of the three Nobel Laureates have revealed how the innate and adaptive phases of the immune response are activated and thereby provided novel insights into disease mechanisms. Their work has opened up new avenues for the development of prevention and therapy against infections, cancer, and inflammatory diseases.

Medicine Nobel to Robert Edwards for IVF

October 4, 2010
SvD: Thirteen minutes before midnight on July 25, 1978 Louise Joy Brown delivered a baby girl by Caesarean section at Oldham General Hospital outside Manchester UK.
The girl weighed 2610 grams and the responsible physician Patrick Steptoe was soon able to reassure the hundreds of journalists gathered that “all studies have shown that the child is completely normal. ” The news of the birth was a medical sensation. Louise Brown was the first child in the world born with the aid of in vitro fertilisation (IVF).

BBC: Robert Edwards, the man who devised the fertility treatment IVF, has been awarded this year’s Nobel prize for medicine. His efforts in the 1950s, 60s and 70s led to the birth of the world’s first “test tube baby” in July 1978. Since then more than four million babies have been born following IVF.

The prize committee said his achievements had made it possible to treat infertility, a medical condition affecting 10% of all couples worldwide.

(That’s one prediction I got wrong)