Peter Alwin wins Electrolux Design Lab 2010

September 23, 2010

Peter Alwin from National Institute of Design in India is the winner of the Electrolux Design Lab 2010 competition for inventing The Snail.

The Snail by Peter Alwin

The Snail by Peter Alwin

The Snail is a portable heating and cooking device based on magnetic induction processes. Such is the size and versatility of the Snail, it can be stuck directly on to a pot, a pan, a mug etc. to heat the contents.This reduces the amount of space required for conventional cooking whilst adding portability to the process. Powered by a high density sugar crystal battery, the Snail converts the energy from the sugar, heating up a coil to conduct the magnetic induction process to the utensil. Integrated sensors detect the food type being heated so as to automatically adjust the time and temperature. A simple touch sensitive display with interface helps to monitor the process.

The top eight finalists

FIRST PLACE: The Snail, Micro Induction Heating by Peter Alwin, National Institute of Design, India

Bio robot refrigerator

SECOND PLACE: Bio Robot Refrigerator, Cool, Green, Food Preservation by Yuriy Dmitriev, CSU, Russia

THIRD PLACE: Elements Modular Kitchen, All-In-One Kitchen Shelving by Matthew Gilbride, North Carolina State University, USA

Elements modular kitchen

PEOPLE’S CHOICE: Bio Robot Refrigerator, Cool, Green, Food Preservation by Yuriy Dmitriev, CSU, Russia

  • The Kitchen Hideaway, by Daniel Dobrogorsky, Monash University, Australia
  • Clean Closet, All in One Laundry Concept by Michael Edenius, Umeå Institute of Design, Sweden
  • Dismount Washer, Wash & Go Laundry by Lichen Guo, Zhejiang University of Technology, China
  • External Refrigerator, External Cooling by Nicolas Hubert, L’Ecole de Design Nantes Atlantique, France
  • Eco Cleaner, the Portable, Compact Dishwasher by Ahi Andy Mohsen, Elm o Sanat University, Iran

See slide show at

http://news.discovery.com/tech/future-appliances-mega-cities-electrolux.html

New Scientist permits the sun to join the climate club

September 23, 2010

It does seem as if the AGW establishment are preparing the ground for admitting that the sun is perhaps critical for climate.

The New Scientist runs an editorial today grudgingly admitting that “The sun’s activity has a place in climate science”.

FOR many years, any mention of the sun’s influence on climate has been greeted with suspicion.

People who believe human activity has no effect on the climate staked a claim on the sun’s role, declaring it responsible for the long-term warming trend in global temperatures. Climate scientists were often uneasy about discussing it, fearful that any concession would be misunderstood by the public and seen as an admission that climate sceptics are right.

No one has ever denied that the sun has an effect on climate. But the consensus view has always been that variations in the sun’s activity, such as the 11-year sunspot cycle, have insignificant effects. While this remains true, the latest findings show that the sun might be significant on a more regional scale. It seems changes in solar activity can have consequences ranging from higher rainfall in the tropics to extreme weather events in the north.

Mighty sun

But then they go out of their way in this article (see “The sun joins the climate club”) to denigrate the sun.

THE idea that changes in the sun’s activity can influence the climate is making a comeback, after years of scientific vilification, thanks to major advances in our understanding of the atmosphere.

The findings do not suggest – as climate sceptics frequently do – that we can blame the rise of global temperatures since the early 20th century on the sun. “There are extravagant claims for the effects of the sun on global climate,” says Giles Harrison, an atmospheric physicist at the University of Reading, UK. “They are not supported.”

Where solar effects may play a role is in influencing regional weather patterns over the coming decades. Predictions on these scales of time and space are crucial for nations seeking to prepare for the future.

Over the famous 11-year solar cycle, the sun’s brightness varies by just 0.1 per cent. This was seen as too small a change to impinge on the global climate system, so solar effects have generally been left out of climate models. However, the latest research has changed this view, and the next report by the Intergovernmental Panel on Climate Change (IPCC), due in 2013, will include solar effects in its models.

But the sun does not much care (Beware the Icarus Syndrome) I think for the scientific establishment and will continue to do its own thing.

Indian fiasco likely at the Commonwealth Games

September 23, 2010

The mess that is the organisation and preparation of the Commonwealth Games to be held in Delhi is going from bad to worse. Every day there are new instances of rampant corruption, new examples of the venal attitude of all the organising committee and the surrounding politicians, collapsing architecture, cases of child labour, withdrawal of athletes and maybe even countries, security fears, uninhabitable and unhygienic athletes accommodation, traffic chaos and now even potential flooding after a prolonged and vigorous monsoon.

India is known for the “last minute” fix but is also known for  the “last mile syndrome” where the final 5% never gets completed. The organising committee and the Delhi politicians are busy pointing fingers and the Central Gov’t has been forced to step in.

Prime Minister Manmohan Singh has stepped in to clear the Commonwealth Games mess. Singh has called Union Sports Minister MS Gill and Union Urban Development Minister Jaipal Reddy for urgent consultations.

A view of the 2010 Commonwealth Games Village in New Delhi. Certain players have asked for a different accodomation as they found the Village 'unliveable.'

2010 Commonwealth Games Village:players have asked for a different accodomation as they found the Village 'unliveable.'

On a day of embarrassment for Delhi and with 11 days to go for the Commonwealth Games, the incomplete and “filthy” Games Village came in for severe criticism from foreign delegates and the Commonwealth Games Federation (CGF).

The finger pointing and posturing is getting ugly. Meanwhile, Congress MP and former Union sports minister Mani Shankar Aiyar has slammed the Commonwealth Games Federation top bosses – Mike Fennell and Mike Hooper saying they have no right to criticise the Games.

This threatens to be a national embarrassment.

I live in hope but whether something can be salvaged from this fiasco remains to be seen.

http://timesofindia.indiatimes.com/sports/events-tournaments/commonwealth-games/top-stories/CWG-mess-PM-steps-in-calls-Gill-Reddy-for-meeting/articleshow/6612183.cms

Stuttgart’s white elephant

September 23, 2010

Hamada Marine "Bridge to Nowhere"

Japan is famous for its bridges to nowhere and highways without traffic but Germany is not immune from this extravagant form of supporting the construction industry and their powerful lobbies.

Der Spiegel runs a scathing attack on the white elephant that is “Stuttgart 21” and Deutsche Bahn‘s CEO Rüdiger Grube:

A multibillion railway development project is going ahead in Stuttgart, despite the fact that it offers hardly any benefits for the rail network and the money would be better spent elsewhere. Experts have been warning against the plans for years, but they were ignored.

Current estimates put the costs of building the subterranean railway station in Stuttgart, the capital of the southwestern German state of Baden-Württemberg, at €4.1 billion ($5.38 billion). An associated high-speed rail line to Ulm, a city lying about 90 kilometers (56 miles) southeast of Stuttgart, is slated to cost another €3 billion.

But what, you might ask, is the payoff for Deutsche Bahn, the federal government or the EU of implementing Stuttgart 21 and building the new line to Ulm? Deutsche Bahn CEO Rüdiger Grube offers one answer: The building project, he explains, will “eliminate the biggest bottleneck on the high-speed route from Paris to Bratislava.”

It would seem that Grube still doesn’t have his facts straight. It might help if he actually took the train from Paris to Bratislava. The roughly 13-hour trip would probably be enough to convince him that this so-called express corridor actually isn’t so express and that boring tunnels through the karst formations of the Swabian Alps mountain range for the Stuttgart-Ulm line is not about to make the connection significantly more attractive.

See map Paris to Bratislava

As Düsseldorf-based engineer Sven Andersen puts it, “Stuttgart 21 does nothing for long-distance travel.” Unlike Grube, Andersen has spent his entire career working in the railway industry, most recently as an expert on operational issues, and is considered one of the top experts on Germany’s railway system.

New Stuttgart station

As Andersen sees it, Stuttgart 21 and the related plan to built the Stuttgart-Ulm high-speed railway line are “a transportation-policy disaster.” Likewise, he adds, the project seems to be based on a complete misunderstanding of Stuttgart’s role in the German and European railway network. “Stuttgart is a destination,” he says. “It’s not a place people travel through to get someplace else. Converting the station into a through station won’t be an improvement on any significant route.” Indeed, all you have to do is look at a map to realize that Stuttgart is not a central location. All fast connections between key economic zones pass through other cities. For example, the Frankfurt-Zurich route runs far west of Stuttgart through Karlsruhe and Basel, while the Frankfurt-Munich route makes a wide arch through Würzburg and Nuremberg, far north and east of Stuttgart.

Full article:

http://www.spiegel.de/international/germany/0,1518,717575,00.html

Human malaria may have come from gorillas (not chimps)

September 23, 2010

It is heartening to see that science generally works and understanding increases as one discovery leads to another and tentative conclusions from one do not stand in the way of coming to new and different conclusions. Solid and painstaking work in the field and the lab (and not like the so-called science where the grabbing of headlines or the chasing of tenure or generation of funds dominates).

Not very long ago (3rd August 2009) the BBC reported that

Common chimpanzee in the Leipzig Zoo.

Image via Wikipedia

” By looking at blood samples, a US team discovered all world strains of the human malaria parasite falciparum stem from a malaria parasite in chimps. They tell Proceedings of the National Academy of Sciences how the species shift probably happened 10,000 years ago when humans turned to agriculture. Although chimps were known to harbour a parasite – Plasmodium reichenowi – that is closely related to the most common of the human malaria parasites, Plasmodium falciparum, many scientists had assumed that the two had co-existed separately. But blood tests on 94 wild and captive chimpanzees in Cameroon and the Ivory Coast suggest falciparum evolved from reichenowi. Francisco Ayala, of the University of California, Irvine, and colleagues found eight new strains of reichenowi that had striking similarities to falciparum and were genetic precursors to the human disease. The leap could have happened as early as two to three million years ago, but most likely to our Neolithic ancestors as recently as 10,000 years ago”.

But further work reported by the BBC yesterday now shows that the human malaria parasite is more likely to have originated with the gorilla parasite.

Gorilla (Nature)

Gorillas may be the source of human cerebral malaria

“Until now, it was thought that the human malaria parasite split off from a chimpanzee parasite when humans and chimpanzees last had a common ancestor. But researchers from the US, three African countries, and Europe have examined malaria parasites in great ape faeces. They found the DNA from western gorilla parasites was the most similar to human parasites.

Malaria is caused by a parasite called Plasmodium, and is carried by mosquitoes. The most common species found in Africa, Plasmodium falciparum, causes dangerous cerebral malaria. Over 800,000 people die from malaria each year in the continent. Until now, scientists had assumed that when the evolutionary tree of humans split off from that of chimpanzees – around five to seven million years ago – so had Plasmodium falciparum. This would have meant that humans and malaria co-evolved to live together. But new evidence suggests human malaria is much newer. Dr Beatrice Hahn of the University of Birmingham, Alabama, in the US, is part of a team that had been studying HIV and related infections in humans and great apes.

To study the DNA of infections in wild apes, you cannot use blood samples. So the team collected 2,700 samples of faecal material from two species of gorilla – western and eastern – and from common chimpanzees and bonobos, also known as pygmy chimpanzees”.

http://www.bbc.co.uk/news/science-environment-11393664


Spring blizzards in New Zealand

September 22, 2010

The Southern Hemisphere is still facing bitterly cold weather.

Southland, New Zealand

The 1st of September is usually designated as the start of spring in New Zealand. Lambing is in full swing but six days of blizzards are being called the worst spring storm in living memory. Cars, lambs, and buildings have all fallen victim to the unusually heavy, wet snow that has fallen in Southland. Seven trampers were rescued by helicopterafter being caught in the snowstorm that has swept South Island national parks. A roof of a stadium collapsed in Southland under the weight of wet snow. A sixth day of snow, rain, wind, hail and sleet was forecast for the already battered coastal belt from Colac Bay in Southland, parts of Central Southland, the Catlins, Owaka and Clinton. Three snowfalls of up to 15cm since Saturday had left ground conditions so wet and muddy that newborn lambs had nowhere dry to go.

A ewe shows concern for her lamb

BARRY HARCOURT/The Southland Times

Exactly how many lambs have been killed will not be known until tailing but at an expected average price of $80 for each lamb, the cost to farmers could be measured in millions of dollars. In recent days, the Owaka Lions Club has collected up to 400 dead lambs a day from the 19km Owaka Valley Rd, for which farmers receive 50c each.

Federated Farmers adverse events spokesman David Rose said he estimated half the farms in Southland were affected. “The spring storm of 2010 is, frankly, the worst in a generation, with farmers going back over 50 years for anything this bad.”

MetService warned that temperatures would plunge in the Southland tonight as a cold front crosses the region. It said significant snowfalls were expected overnight, mainly above 200m, where 10-15cm is possible, especially in the Catlins and hilly areas exposed to strong southwesterlies. Localised blizzards and snow drifts are possible. The Fire Service in Invercargill said it had been flat out working three pumps to drain properties around the city swamped by melting snow.

The North Island has also received its share of the snow fall.

The Rimutaka Hill Road was closed following 2-6cm of snow accumulating on the hill above 400m from 3am to 7am this morning. It has since reopened with cars only allowed across in escorted convoys, one way at a time. The Manawatu Gorge road has reopened following a slip which closed it yesterday. Snow is also falling on the Central Plateau this morning, with 4-12cm accumulating on the Desert Road between 3am and 12am this morning. Another 3-6cm are expected over the next couple of hours. Drivers are warned the road may close.

Sources: http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=10675265

http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=10675510

Harvard President says Hauser could lose tenure

September 22, 2010
Statue of John Harvard, founder of Harvard Uni...

John Harvard: Wikipedia

The Boston Globe reports on an interview of Harvard’s President Drew Gilpin Faust by former ABC correspondent Charlie Gibson.

The discussion, billed as a start-of-the-school year address, was held at Sanders Theatre and broadcast over the Internet. In response to Gibson’s question about why Marc Hauser remained on the faculty even after the university found him guilty of eight instances of scientific misconduct, Faust said Harvard is addressing the issue. “Integrity is absolutely fundamental in everything we do,’’ Faust said. “We have a process we have undertaken, and that process still has some part to continue because it involves federal funds.’’ Cases of scientific misconduct could result in a loss of tenure, Faust said.

Gibson said the silence from the university has been “somewhat deafening,’’ and raised the possibility that the lack of response could call into question Harvard’s research integrity and have financial implications. But Faust replied that Harvard has moved to depart somewhat from its normally confidential proceedings, in order to correct the scientific record, though it remains mindful of ongoing federal investigations. “Announcing that there were indeed findings, that was unprecedented,’’ she said.

Whether the Harvard President is actually trying to maintain and protect integrity or merely engaging in damage control is unclear. The second part of the Boston Globe article is about the honouring of Martin Peretz and how Harvard is swallowing its principles and seems to show that there is a price at which Harvard is prepared to compromise integrity.

But meanwhile the wagons continue to circle.

Bert Vaux who is a former Professor of Linguistics at Harvard University and Jeffrey Watumull who is a PhD student in Linguistics and a member of Hauser’s lab have rushed to his defence in The Harvard Crimson.

“In our experience, Marc Hauser is the consummate scientist—the most disinterested, the most rational, the most ethical. We are proud to be his colleagues. However, we are less than proud of those in the cognitive sciences reacting publicly to Hauser’s case with irresponsible impatience (disrespect for due process), unjustified slurs, and half-baked conjectures. All are interested in the truth, but as scientists we ought to consider the case reasonably and measuredly, with objectivity and fairness”.

But they forget that his nonsense started at least as long ago as 1995. One wonders whether Hauser’s defenders are part of a concerted damage control exercise. Methinks they do protest too much.

The onus of proof has shifted.

Habitable planet to be discovered in May 2011?

September 22, 2010

The only thing certain about forecasts is that they are more often wrong than right – and I exclude forecasts made entirely on known science or “laws” of nature where the level of uncertainty is insignificant (e.g. the sun will rise tomorrow). Nevertheless “Future History” which is a study of how forecasts evolve and how accurate they have been is a most powerful tool when making judgements about directions to follow and actions to be taken. In management “Future History” methodology is, I think, one of the most powerful tools for the development of corporate strategies and action plans.

The New Scientist reports that :

“Two researchers have used the pace of past exoplanet finds to predict that the first habitable Earth-like planet could turn up in May 2011”.

In 1965, Intel co-founder Gordon Moore observed that the number of transistors that fit on a chip doubles about once every two years – a trend now known as Moore’s law. Samuel Arbesman of Harvard Medical School in Boston wants to see if scientometrics – the statistical study of science itself – can similarly be used to not only study past progress but also to make predictions.

He and Greg Laughlin of the University of California, Santa Cruz, are testing the idea with exoplanets. Over the past 15 years or so, the pace of planet discoveries has been accelerating, with some 490 planets now known. “It is actually somewhat similar to Moore’s law of exponential growth,” Arbesman says.

To predict when astronomers might find the first planet similar in size to Earth that also orbits far enough from its star to boast liquid water, the team scoured the discovery records of 370 exoplanets.

They focused on two basic properties needed for habitability: a planet’s mass and its surface temperature. They used these two factors to assign each planet a ‘habitability metric’ ranging from 0 to 1, where 0 was uninhabitable and 1 is close to Earth’s twin.

A rough estimate of each planet’s habitability was then plotted against the date of its discovery. Using different subsets of the 370 planets, the researchers made curves from the individual points and extrapolated the curves to find when a planet would be found with a habitability of 1. They then analysed the range of discovery dates to determine which would be most probable.

Habitable planets: http://t2.gstatic.com/images

Their calculations suggest there is a 50 per cent chance that the first habitable exo-Earth will be found by May 2011, a 75 per cent chance it will be found by 2020, and a 95 per cent chance it will be found by 2264.

In fact, exoplanet researchers have made forecasts of the future informally, plotting the mass of planets against the date of discovery to see how the field is progressing. “We’ve done that for many years at conferences,” says Eric Ford of the University of Florida in Gainesville. “The new aspect of this paper is putting an uncertainty on those predictions and unfortunately the uncertainty is quite large.”

One source of uncertainty is how factors like changes in funding and the development of new techniques and technology can alter the pace of discovery. “Like the stock market, past returns are no guarantee of future performance,” Ford says.

“There are always these complex factors of how science is actually done,” Arbesman agrees. But he says the forecasting technique could still prove useful, even if these factors are not accounted for directly. In part, that is because new technologies tend to take a while to ramp up, so they may not lead to sharp jumps in the number of discoveries made.

Previously, Arbesman has quantified how the ease of discovering new mammalian species, chemical elements, and asteroids affects the rate of their discovery. New species and asteroids are more difficult to find the smaller they are, and indeed larger ones are found first. For chemical elements, the opposite is true, since the bigger they are, the rarer and more unstable they tend to be.

Chilies: The real difference between humans and animals

September 22, 2010

As Paul Bloom, a Yale psychologist, puts it, “Philosophers have often looked for the defining feature of humans — language, rationality, culture and so on. I’d stick with this: Man is the only animal that likes Tabasco sauce.”

Chilies

From the New York Times:

Indian Jolokia pepper

Jolokia chili

Habaneros are very hot, although there’s a lot of variation. On the standard Scoville heat scale (Bell peppers 0, the hottest Indian jolokia peppers 1,000,000) orange habaneros run 100,000 to 350,000. By comparison, jalapenos can go anywhere from 5,000 to 50,000. Two percent capsaicin bear spray is advertised at 3.3 million units, and pure capsaicin — the chemical that causes the pain — hits 16 million.

Some experts argue that we like chilies because they are good for us. They can help lower blood pressure, may have some antimicrobial effects, and they increase salivation, which is good if you eat a boring diet based on one bland staple crop like corn or rice. The pain of chilies can even kill other pain, a concept supported by recent research.

I can identify with this.  Bring on the vengaya chutney.

My Vengaya chutney:

Vengaya chutney

2 large onions, a fistful of dried red (Indian) chilies, a chunk of ginger, 4 cloves of garlic, 2 Habanero chilies.

Blend together into a paste. Add chilies to suit for colour and heat.

Garnish with a teaspoon each of mustard seeds and urad dal, 2 bay leaves heated for 90 seconds in hot oil.

Serve as relish on anything and with everything.

  • Spread on bread and serve grilled or roasted
  • spread on bread when making sandwiches
  • add a teaspoon to any soup (or any gravy for that matter)
  • spread on any meat before grilling (or after grilling if you prefer the raw heat)
  • add a tablespoon while tossing pasta
  • eat traditionally as an accompaniment to idlis and dosais.

The NYT continues:

Others, notably Dr. Paul Rozin at the University of Pennsylvania, argue that the beneficial effects are too small to explain the great human love of chili-spiced food. “I don’t think they have anything to do with why people eat and like it,” he said in an interview. Dr. Rozin, who studies other human emotions and likes and dislikes (“I am the father of disgust inpsychology,” he says) thinks that we’re in it for the pain. “This is a theory,” he emphasizes. “I don’t know that this is true.”

But he has evidence for what he calls benign masochism. For example, he tested chili eaters by gradually increasing the pain, or, as the pros call it, the pungency, of the food, right up to the point at which the subjects said they just could not go further. When asked after the test what level of heat they liked the best, they chose the highest level they could stand, “just below the level of unbearable pain.” As Delbert McClinton sings (about a different line of research), “It felt so good to hurt so bad.”

The story of how chilies got their heat is pretty straightforward. A recent study suggested that capsaicin is an effective defense against a fungusthat attacks chili seeds. In fact, experiments have shown that the same species of wild chili plant produces a lot of capsaicin in an environment where the fungus is likely to grow, and very little in drier areas where the fungus is not a danger.

The fact that capsaicin causes pain to mammals seems to be accidental. There’s no evolutionary percentage in preventing animals from eating the peppers, which fall off the plant when ripe. Birds, which also eat fruits, don’t have the same biochemical pain pathway, so they don’t suffer at all from capsaicin. But in mammals it stimulates the very same pain receptors that respond to actual heat. Chili pungency is not technically a taste; it is the sensation of burning, mediated by the same mechanism that would let you know that someone had set your tongue on fire.

No one knows for sure why humans would find pleasure in pain, but Dr. Rozin suggests that there’s a thrill, similar to the fun of riding a roller coaster. “Humans and only humans get to enjoy events that are innately negative, that produce emotions or feelings that we are programmed to avoid when we come to realize that they are actually not threats,” he said. “Mind over body. My body thinks I’m in trouble, but I know I’m not.” And it says, hand me another jalapeño.

Other mammals have not joined the party. “There is not a single animal that likes hot pepper,” Dr. Rozin said. Or asPaul Bloom, a Yale psychologist, puts it, “Philosophers have often looked for the defining feature of humans — language, rationality, culture and so on. I’d stick with this: Man is the only animal that likes Tabasco sauce.”

As James Gorman, the author of the NYT article puts it:

A taste for chilies has no deep meaning, no evolutionary value. It’s just a taste for chilies. I might add, though, that since it takes such a complicated brain and weird self-awareness to enjoy something that is inherently not enjoyable, only the animal with the biggest brain and the most intricate mind can do it. Take heart, chili heads. It’s not dumb to eat the fire, it’s a sign of high intelligence.

After Harvard’s Hausergate, now misconduct at Mount Sinai

September 21, 2010
Mount Sinai School of Medicine logo.png

Image via Wikipedia

Earlier this week, the blog Retraction Watch called attention to four recent paper retractions by noted gene therapy researcher Savio Woo of Mount Sinai School of Medicine in New York City. Today, the school said in a statement that two of Woo’s postdoctoral fellows have been fired for research misconduct and that an internal investigation has cleared Woo of any wrongdoing.

Two of Woo’s post-doctoral fellows at Mount Sinai School of Medicine were dismissed for “research misconduct,” said Ian Michaels, a spokesman for the institution. According to Michaels:

When Dr. Savio L C Woo came to suspect that two post-doctoral fellows in his laboratory may have engaged in research misconduct he notified the Mount Sinai Research Integrity Office. Mount Sinai immediately initiated institutional reviews that resulted in both post-doctoral fellows being dismissed for research misconduct. At no time were there allegations that Dr. Woo had engaged in research misconduct. As part of its review, the investigation committee looked into this possibility and confirmed that no research misconduct could be attributed to Dr. Woo, who voluntarily retracted the papers regarding the research in question. Mount Sinai reported the results of its investigations to the appropriate government agencies and continues to cooperate with them as part of its commitment to adhere to the highest standards for research integrity.

File:HippocraticOath.jpg

Wikipedia: A twelfth-century Byzantine manuscript of the Hippocratic Oath.

According to ScienceInsider, the names of postdocs Li Chen and Zhiyu Li were recently removed from Mount Sinai’s directory. Chen and Li were listed as first authors on the retracted papers. Three  major journals — Proceedings of the National Academy of SciencesHuman Gene Therapy, and the Journal of the National Cancer Institute — recently retracted papers authored by Woo and others.

In a retraction notice issued this month, Woo wrote that:

It was discovered that some of the micrographs in two papers we published [figure 4 in J Natl Cancer Inst 2008;100:1389-1400 (1), and figure 3 in Hum Gene Ther 2009;20:751-758 (2)] are apparently duplicated. This has been reported to the institutional research integrity committee by the authors and while the outcome of an investigation is pending, the undersigned co-authors respectfully request a retraction of both papers and sincerely apologize to our colleagues.

The four papers in question focus on two different areas of gene therapy research. One pair, published in 2008 in the Journal of the National Cancer Institute and in 2009 in Human Gene Therapy, investigate genetically engineered bacteria as a weapon against cancer. The other two papers describe a method for using bacterial enzymes to introduce therapeutic genes. A 2005 paper in the Proceedings of the National Academy of Sciences reports experiments in which mice with the metabolic disorder phenylketonuria appeared to be cured using this method. As a demonstration of the promise of gene therapy, that work garnered some media coverage, includingthis article in Science. A 2008 paper in Human Gene Therapy described the use of the technique in human cells.

Source: http://blog.the-scientist.com/2010/09/20/new-in-a-nutshell/